Category : Business Post
Seems like there’s always something new in the fitness game, and despite the fact that GW-501516 is now under the spotlight, it’s actually been on the market since the early 1990s. Bodybuilders even call it the ultimate performance enhancer. Simply said, it’s a chemical substance that activates the peroxisome proliferator activator receptor delta, or for short – PPAR delta. And if you’re wondering what that is – it’s a transcription factor that increases the expression of multiple different genes.
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<p>Cardarine (GW501516) is a PPAR (Peroxisome proliferator-activated receptor) drug, which is also sold and marketed as a SARM (selective androgen receptor modulator). This drug started being researched in the early 1990’s by GlaxoSmithKline and Ligand Pharmaceuticals to treat diabetes, obesity, and heart disease.</p>
<p>Cardarine (GW-501516) first was developed in the early 1990’s by Ligand and GlaxoSmithKline as an anti-tumor drug. They also found out it worked well for lipid/heart health during the early trials and then how effective it was for endurance, diabetes, and getting rid of fat.</p>
<p>GW501516 (GW1516 or GSK-516) is often a drug that acts as a PPARd modulator. GW 501516 activates AMP-activated protein kinase and stimulates glucose uptake in skeletal muscle tissue, and GW 501516 has been demonstrated to reverse metabolic abnormalities in obese guys with pre-diabetic metabolic syndrome, probably by stimulating fatty acid oxidation.</p>