Sabrina Rey
February 17, 2016 

Aldehyde Dehydrogenase

Aldehyde Dehydrogenase

Category : Health And Fitness

Aldehyde dehydrogenase from yeast catalyzes the following reaction: RCHO + NAD/NADP+ + H2O → RCOOH + NADH/NADPH+ + H+. The yeast enzyme requires potassium ions and thiols (glutathione, 2-mercaptoethanol, cysteine) for its activity. It is inhibited by traces of heavy metals, particularly copper. Similar enzymes, but with different requirements for their catalytic activities, have been purified from equine liver and from human erythrocytes. The enzyme from yeast has a molecular weight of 200,000.

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