Have you heard of a unique protein called brain-derived neurotrophic factor (BDNF)?
This protein exists in our brain and plays a vital role in our central and peripheral nervous system. Without BDNF, our neurons and synapses cannot survive, operate or grow in the normal way. In addition, BDNF is also active in the brain area responsible for learning, memory and advanced thinking.
One study showed that BDNF was associated with depression because BDNF expression was lower in patients with depression. Suicide is also associated with lower BDNF expression, which may not be related to depression.
Therefore, maintaining the average BDNF level is essential to combat anxiety and depression. Fortunately, this is where selank can intervene and help.
According to the study, selank peptide can regulate the expression of BDNF in rat hippocampus when administered intranasal. Specifically, at a dose of 250 or 500 µ g/kg body weight, selank significantly increased the level of BDNF protein in the hippocampus after 3 hours of administration.
The results showed that selank with anti-anxiety and intellectual properties could regulate the BDNF level in rat hippocampus.
Selank peptide benefits
Promote relaxation and reduce anxiety
As mentioned above, selank can effectively promote relaxation and reduce anxiety and depression by correcting serotonin metabolism and increasing BDNF expression.
In fact, selank has been studied in Russia for the treatment of generalized anxiety disorder (GAD).
The study found that the effect of selank was similar to that of another drug "medazepam" used to treat anxiety. In the United States, Medazepam is a long-acting and rarely prescribed benzodiazepine drug, an anti-anxiety drug used to treat anxiety and panic disorder.
However, the advantages of selank peptide are superior, because it also has anti-neurasthenic and mental stimulation effects.
Improve cognitive functions, such as memory
For a long time, anxiety, learning and memory have been linked together.
This correlation is the opposite. Increased anxiety will lead to a decline in the ability to recall or store new information.
Although it is obvious that selank can improve cognitive functions such as learning and memory by reducing anxiety, some people believe that selank can directly and independently improve cognition.
According to the research, selank improved the memory stability of rats, thus improving the memory storage process. It is noteworthy that this benefit has been observed regardless of the anxiety level of rats, which indicates that the role of peptide is not only to reduce the memory impairment caused by stress.
But how does selank affect memory independently of anxiety?
Selank seems to affect memory by affecting the expression of specific genes in the hippocampus. Selank can even help restore memory and learning ability after brain injury. In at least one study, the cognitive process of rats with nerve injury recovered after receiving selank. This effect seems to be related to the artificial inhibition of brain catecholamine system by selank.
Selenk peptide dosage
Selank is a nasal drop administered through the nostrils.
This drug can only be used on the nose, because saliva is easily decomposed in the digestive system and loses its effectiveness.
In contrast, when inhaled through the nostrils, selank is more likely to be absorbed through the blood-brain barrier and have an anti-anxiety effect on our nervous system.
So how much medicine should you take?
According to the anecdote, you can drop 2-3 drops of selank into each nostril every day, up to 3 times. Selank treatment lasts for 2 weeks and can be repeated after 1-3 weeks until the condition improves.
Side effects of Selank peptide
So far, research on selank has shown the least side effects.
Clinical research shows that selank is similar to low-dose sedatives, but it has no adverse side effects of sedatives, such as amnesia, withdrawal and dependence.
In conclusion, more clinical studies are needed to fully determine the benefits of selank peptide and its side effects on human body. Before that, we may have more alternative methods to treat anxiety to help patients get rid of mental disorders most effectively.
